Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 3-Aminoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | 3-Nitroquinoline | HCID 25551 | — |
| 촉매 | Iron | HCID 23925 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 촉매 | Zinc | HCID 23994 | — |
| 촉매 | Platinum oxide (PtO) | HCID 82844 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Aminoquinoline | HCID 11375 | — |
반응 단계
The 3-nitroquinoline derivative of the formula (c) is then catalytically reduced in an inert solvent such as ethanol, ethyl acetate, methanol or THF, using platinum oxide or palladium/carbon, or reduced by iron or zinc and acetic acid or tin (II) chloride, to give the 3-aminoquinoline derivative of the formula (d).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05693651 |
| 출처 데이터셋 | uspto-grants-1997_12 |
| ORD ID | ord-8821263ce0054d48b38ee0adbffc7235 |
| 출처 메모 | uspto-grants-1997_12 |