Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 2-Nitro-4-morpholinocarbonylaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | Benzoic acid, 4-amino-3-nitro- | HCID 74115 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-Nitro-4-morpholinocarbonylaniline | HCID 20553752 | — |
반응 단계
A mixture of 4-amino-3-nitrobenzoic acid (7.40 g), 1-hydroxybenzotriazole (6.59 g) , dicyclohexylcarbodiimide (10.90 g) , dry N,N-dimethylformamide (74 ml), and morpholine (4.3 ml) was stirred at room temperature for 2 hours. The insolubles were filtered out, and washed with N,N-dimethylformamide. The filtrate and the washing were combined, and concentrated to obtain a yellowish brown solid (16.01 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05696118 |
| 출처 데이터셋 | uspto-grants-1997_12 |
| ORD ID | ord-bfc95523844a4f849ce33eac158cbab0 |
| 출처 메모 | uspto-grants-1997_12 |