Picolyl chloride → HCID 53710724, 화합물

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[O:1]([CH2:9][CH2:10][CH:11]1[C:16](=[O:17])[NH:15][C:14]2[CH:18]=[CH:19][CH:20]=[CH:21][C:13]=2[O:12]1)[Si](C(C)(C)C)(C)C.Cl[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=1>>[OH:1][CH2:9][CH2:10][CH:11]1[C:16](=[O:17])[N:15]([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=2)[C:14]2[CH:18]=[CH:19][CH:20]=[CH:21][C:13]=2[O:12]1

참가 물질

반응물 2

HCID 23393Picolyl chloride

HCID 120480202-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]-2H-1,4-benzoxazin-3(4H)-one

생성물 1

HCID 53710724HCID 53710724, 화합물

실험 절차

2-(2-tert-Butyldimethylsiloxyethyl)-3,4-dihydro-3-oxo-2H-1,4-benzoxazine was alkylated with 2-chloromethylpyridine by method F and the crude product was deprotected by method H without purification.

후처리

customthe crude product was deprotected by method H without purification

출처 및 근거

ORD 기록: ord-d7362c82d4474ee1a876df8ba3b927bd
출처 데이터셋: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05696117

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