HCID 265049, 화합물 → 3-aminophenanthridin-6(5h)-one

HRID 1939426노트

반응식

HRID 1939426 반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:8]3[C:13]([C:14](=[O:18])[NH:15][C:16]=2[CH:17]=1)=[CH:12][CH:11]=[CH:10][CH:9]=3)([O-])=O>CN(C=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[C:8]3[C:13]([C:14](=[O:18])[NH:15][C:16]=2[CH:17]=1)=[CH:12][CH:11]=[CH:10][CH:9]=3

참가 물질

4

반응물 1

HCID 265049HCID 265049, 화합물

생성물 1

HCID 2690393-aminophenanthridin-6(5h)-one수율 126.8%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 6228Dimethylformamide용매

실험 절차

A mixture of 3-nitro-6(5H)-phenanthridinone (structure 55 of Scheme XVI, where R1 =H, R2 =R3 =benzo, Y=NH) (480 mg, 1.5 mmol) and 50 mg of 10% Pd/C in 60 mL of DMF was stirred under an atomsphere of H2 for 2 h. The mixture was filtered through a Celite™ pad and the filtrate was concentrated to give 0.4 g of the crude aniline as a yellow solid. This material was used without further purification.

후처리

  1. filtrationThe mixture was filtered through a Celite™ pad
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-b0c12561e5284c65a7223ffc349063b1
출처 데이터셋
uspto-grants-1997_12
특허 번호
US05696127

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