Water → (+)-2-Octanol
반응식
[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]CCCC(OC)=O)(OC)=O.[OH2:19]>>[CH3:1][C@H:5]([OH:19])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]참가 물질
3
실험 절차
Interesterification was carried out in the same manner as in Example 13, except for replacing dimethyl tetradecadicarboxylate with 140 g of dimethyl decamethylenedicarboxylate at 80° C. for 25 hours. The water content of the reaction system was 0.04% by weight, and 95% of the lipase particles had a particle size of 20 to 60 μm. Gas chromatography of the reaction mixture revealed that 58 mol % of (R,S)-2-octanol had been converted to its decamethylenedicarboxylic acid esters. The reaction mixture was treated in the same manner as in Example 13 to remove lipase, and the filtrate was subjected to simple distillation at 95° C. and 3 mmHg. It was impossible to isolate (S)-(-)-2-octanol with high purity due to co-distillation of other components.
후처리
- customat 80° C.
- customfor 25 hours
- additionThe reaction mixture was treated in the same manner as in Example 13
- customto remove lipase