Ethanol → 2,4-D-ethyl
반응식
OS(O)(=O)=O.[Cl:6][C:7]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:8]=1[O:9][CH2:10][C:11]([OH:13])=[O:12].[CH2:19](O)[CH3:20]>>[Cl:6][C:7]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:8]=1[O:9][CH2:10][C:11]([O:13][CH2:19][CH3:20])=[O:12]참가 물질
4
실험 절차
1.3 g (14 mmol) of H2SO4 were added to 15.0 g (68 mmol) of 2,4-dichlorophenoxyacetic acid in 20 ml of ethanol, and the mixture was refluxed for 5 hours. The mixture was subsequently concentrated in vacuo, the residue was poured into 100 ml of ice-water, the organic phase was separated off, and the aqueous phase was extracted using ether. The combined organic phases were washed using 2N Na2CO3 solution and water, dried over magnesium sulfate and concentrated. 8.9 g (53% of theory) of ethyl 2,4-dichlorophenoxyacetate were obtained as a colorless oil.
후처리
- temperaturethe mixture was refluxed for 5 hours
- concentrationThe mixture was subsequently concentrated in vacuo
- additionthe residue was poured into 100 ml of ice-water
- customthe organic phase was separated off
- extractionthe aqueous phase was extracted
- washThe combined organic phases were washed
- dry with materialdried over magnesium sulfate
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-33504bd217a745aa92858c5740299f06
- 출처 데이터셋
- uspto-grants-1997_12
- 특허 번호
- US05698539
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