3-Methylisoxazole-5-carboxylic acid → HCID 21465238, 화합물

HRID 1939934노트

반응식

HRID 1939934 반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:13]=[CH:14][C:15](=[O:18])[NH:16][N:17]=2)=[CH:8][CH:7]=1.[CH3:19][C:20]1[CH:24]=[C:23]([C:25](O)=[O:26])[O:22][N:21]=1>>[CH3:19][C:20]1[CH:24]=[C:23]([C:25]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]2[CH:7]=[CH:8][C:9]([C:12]3[CH:13]=[CH:14][C:15](=[O:18])[NH:16][N:17]=3)=[CH:10][CH:11]=2)=[O:26])[O:22][N:21]=1

참가 물질

3

반응물 2

HCID 8530853-Methylisoxazole-5-carboxylic acidHCID 18977179HCID 18977179, 화합물

생성물 1

HCID 21465238HCID 21465238, 화합물

실험 절차

By treating 6-[4-(4-aminobutyl)phenyl]pyridazin-3(2H)-one and 3-methyl-5-carboxyisoxazole in the same manner as in Example 87, 6-{4-[4-(3-methylisoxazole-5-ylcarbonylamino)butyl]phenyl}pyridazin-3(2H)-one was obtained.

출처 및 근거

ORD 기록
ord-f1890c157d1e46828f04faf012146994
출처 데이터셋
uspto-grants-1997_12
특허 번호
US05698554

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