Cyclohexene → (2-Amino-5-hydroxyphenyl)acetonitrile

HRID 1941534노트

반응식

HRID 1941534 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10]CC2C=CC=CC=2)=[CH:6][C:5]=1[CH2:18][C:19]#[N:20])([O-])=O.C1CCCCC=1>[Pd].C(O)C>[C:19]([CH2:18][C:5]1[CH:6]=[C:7]([OH:10])[CH:8]=[CH:9][C:4]=1[NH2:1])#[N:20]

참가 물질

5

반응물 2

HCID 8079CyclohexeneHCID 14025389HCID 14025389, 화합물

생성물 1

HCID 19607200(2-Amino-5-hydroxyphenyl)acetonitrile

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A suspension of 5.4 g of 2-nitro 5-benzyloxyphenylacetonitrile, 5.4 ml of cyclohexene, 22 ml of ethanol and 3 g of 10% palladium on activated charcoal was refluxed for five hours. The suspension was then hot filtered and the filtrate evaporated. The residue was recrystallised from ethanol to produce dark beige crystals.

후처리

  1. temperaturewas refluxed for five hours
  2. filtrationThe suspension was then hot filtered
  3. customthe filtrate evaporated
  4. customThe residue was recrystallised from ethanol
  5. customto produce dark beige crystals

출처 및 근거

ORD 기록
ord-9f85d6aa879d4d139c24221fd3f34af8
출처 데이터셋
uspto-grants-1997_12
특허 번호
US05703266

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