2-Oxazolidinone → 3-(5-Phenylethynyl-pyridin-2-ylmethyl)-oxazolidin-2-one

반응식

[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15]O)=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:17]1[CH2:21][CH2:20][NH:19][C:18]1=[O:22]>>[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][N:19]3[CH2:20][CH2:21][O:17][C:18]3=[O:22])=[N:13][CH:14]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

반응물 2

HCID 739492-Oxazolidinone

HCID 57517077(5-Phenylethynyl-pyridin-2-yl)-methanol

생성물 1

HCID 529171103-(5-Phenylethynyl-pyridin-2-ylmethyl)-oxazolidin-2-one

실험 절차

The title compound, white solid, MS: m/e=279.2 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from (5-phenylethynyl-pyridin-2-yl)-methanol (example 31, step 1) and oxazolidin-2-one.

출처 및 근거

ORD 기록: ord-1741403d8f074f81839d64dcd2fc03fe
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08389536B2

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