4-Heptanol, 1,1,1,7,7,7-hexafluoro- → 1,1,1,7,7,7-Hexafluoro-4-heptanone

HRID 1942309노트

반응식

HRID 1942309 반응식
[F:1][C:2]([F:14])([F:13])[CH2:3][CH2:4][CH:5]([OH:12])[CH2:6][CH2:7][C:8]([F:11])([F:10])[F:9].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[F:1][C:2]([F:13])([F:14])[CH2:3][CH2:4][C:5](=[O:12])[CH2:6][CH2:7][C:8]([F:10])([F:11])[F:9]

참가 물질

4

반응물 2

HCID 538257994-Heptanol, 1,1,1,7,7,7-hexafluoro-HCID 178418287HCID 178418287, 화합물2회

생성물 1

HCID 5805611,1,1,7,7,7-Hexafluoro-4-heptanone

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

1,1,1,7,7,7-Hexafluoroheptan-4-ol (1.4 g, 6.25 mmol) was dissolved in CH2Cl2 (12 mL) and pyridinium chlorochromate (PCC) (1.48 g, 6.87 mmol) was added. The mixture was stirred for 4 h. Additional PCC (800 mg) was added and the mixture stirred for 1 h. The mixture was filtered through celite and silica, washing with DCM. The resulting pale yellow solution was evaporated at room temperature to afford the title compound.

후처리

  1. stirringthe mixture stirred for 1 h
  2. filtrationThe mixture was filtered through celite and silica
  3. washwashing with DCM
  4. customThe resulting pale yellow solution was evaporated at room temperature

출처 및 근거

ORD 기록
ord-f3cbb7be50b041a6a8f31574d5bc39fc
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08389547B2

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