3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (4,4-diethoxy-butyl)-amide → 3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (4-oxo-butyl)-amide

반응식

C([O:3][CH:4](OCC)[CH2:5][CH2:6][CH2:7][NH:8][C:9]([N:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10])C.O=CCCCNC(C1CCCCC1)=O>>[O:3]=[CH:4][CH2:5][CH2:6][CH2:7][NH:8][C:9]([N:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10]

참가 물질

반응물 2

HCID 669374713,4-Dihydro-1H-isoquinoline-2-carboxylic acid (4,4-diethoxy-butyl)-amide

HCID 85725969Cyclohexanecarboxylic acid (4-oxo-butyl)-amide

생성물 1

HCID 866513033,4-Dihydro-1H-isoquinoline-2-carboxylic acid (4-oxo-butyl)-amide

실험 절차

3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (4-oxo-butyl)-amide is prepared from 24B as described for 20B.

출처 및 근거

ORD 기록: ord-bb5d89ad1e5c41ee81a7b9c835c4252c
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08389555B2

반응 노트

불러오는 중…