N-(4-oxo-butyl)-benzamide → 1,3-Dihydro-isoindole-2-carboxylic acid (4-oxo-butyl)-amide

반응식

[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10]1)=[O:8].O=CCCCNC(=O)C1C=CC=CC=1>>[O:1]=[CH:2][CH2:3][CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:10][C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:17]1)=[O:8]

참가 물질

반응물 2

HCID 10352536N-(4-oxo-butyl)-benzamide

HCID 669375761,3-Dihydro-isoindole-2-carboxylic acid-(4-hydroxybutyl)amide

생성물 1

HCID 866513061,3-Dihydro-isoindole-2-carboxylic acid (4-oxo-butyl)-amide

실험 절차

1,3-Dihydro-isoindole-2-carboxylic acid (4-oxo-butyl)-amide (27C) is prepared from 27B as described for 1E. The crude product is obtained in almost quantitative yield.

출처 및 근거

ORD 기록: ord-6f0c773f18044ac8a4e31ecdb91d83f2
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08389555B2

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