1,2,3,6-Tetrahydro-4-phenylpyridine → 4-Phenyl-3,6-dihydro-2H-pyridine-1-carbonyl chloride

HRID 1942375노트

반응식

HRID 1942375 반응식
[C:1]1([C:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C2C(=CC=CC=2)CCN1[C:23]([Cl:25])=[O:24]>>[C:1]1([C:7]2[CH2:12][CH2:11][N:10]([C:23]([Cl:25])=[O:24])[CH2:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 825531,2,3,6-Tetrahydro-4-phenylpyridineHCID 218905713,4-Dihydroisoquinoline-2(1H)-carbonyl chloride

생성물 1

HCID 858108644-Phenyl-3,6-dihydro-2H-pyridine-1-carbonyl chloride수율 95%

실험 절차

4-Phenyl-3,6-dihydro-2H-pyridine-1-carbonyl chloride (62A) is prepared from 4-phenyl-1,2,3,6-tetrahydropyridine as described for 24A.

출처 및 근거

ORD 기록
ord-94146f3766b54bbd9bb48c3e63892b56
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08389555B2

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