1,2,3,4-Tetrahydroisoquinoline → 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)ethan-1-ol

HRID 1942428노트

반응식

HRID 1942428 반응식
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1.C[O:12][C:13]1C=CC=C[C:14]=1N1CCN(CCO)CC1>>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[CH2:14][CH2:13][OH:12]

참가 물질

3

반응물 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 111073541-Piperazineethanol, 4-(2-methoxyphenyl)-

생성물 1

HCID 2462882-(1,2,3,4-Tetrahydroisoquinolin-2-yl)ethan-1-ol수율 60%

실험 절차

2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethanol (31A) is prepared from 1,2,3,4-tetrahydro-isoquinoline as described for 28A.

출처 및 근거

ORD 기록
ord-b59b34ec7b47479891af171141efbd2f
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08389555B2

반응 노트

불러오는 중…