1-Piperazineethanol, 4-(2-methoxyphenyl)- → 2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethan-1-ol

HRID 1942430노트

반응식

HRID 1942430 반응식
Cl.[Cl:2][C:3]1[C:8]([Cl:9])=[CH:7][CH:6]=[CH:5][C:4]=1[N:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1.C[O:17][C:18]1C=CC=C[C:19]=1N1CCN(CCO)CC1>>[Cl:2][C:3]1[C:8]([Cl:9])=[CH:7][CH:6]=[CH:5][C:4]=1[N:10]1[CH2:15][CH2:14][N:13]([CH2:19][CH2:18][OH:17])[CH2:12][CH2:11]1

참가 물질

3

반응물 2

HCID 111073541-Piperazineethanol, 4-(2-methoxyphenyl)-HCID 116303721-(2,3-Dichlorophenyl)piperazine hydrochloride

생성물 1

HCID 198712732-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethan-1-ol수율 97%

실험 절차

2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]ethanol (35A) is prepared from 1-(2,3-dichloro-phenyl)-piperazine hydrochloride as described for 28A.

출처 및 근거

ORD 기록
ord-ecfdd5cb0b9744d3913a74f65cf80767
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08389555B2

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