Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenol → (2,2-Diethoxyethoxy)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Chloro-1,1-diethoxyethane | HCID 12128 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | (2,2-Diethoxyethoxy)benzene | HCID 96328 | — |
반응 단계
0.94 g (10 mmol) of phenol, 1.52 g (10 mmol) of chloroacetaldehyde diethyl acetal, 2.77 g (20 mmol) of potassium carbonate, 500 mg of potassium iodide and 5 ml of dimethylformamide were heated for 1 hour at 175° C. under microwave conditions. The mixture was then diluted with 2M aqueous sodium hydroxide solution and extracted with dichloromethane. The organic layer was dried with sodium sulfate and the solvent evaporated in vacuum. The crude product was obtained in almost quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08389555B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-907d57b1e0434595b23a759968da1805 |
| 출처 메모 | uspto-grants-2013_03 |