4-(4-Methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid → HCID 58375928, 화합물
반응식
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[C:12]2[CH:13]=[C:14]([C:21]([OH:23])=O)[C:15]([C:17]([F:20])([F:19])[F:18])=[CH:16][C:11]=2[O:10][C:9]([CH3:25])([CH3:24])[C:8]1=[O:26].[CH:27]([NH:30][CH:31]1[CH2:35][CH2:34][N:33]([C:36]([O:38][CH2:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)=[O:37])[CH2:32]1)([CH3:29])[CH3:28]>>[CH:27]([N:30]([C:21]([C:14]1[C:15]([C:17]([F:20])([F:18])[F:19])=[CH:16][C:11]2[O:10][C:9]([CH3:25])([CH3:24])[C:8](=[O:26])[N:7]([CH2:6][CH2:5][CH2:4][CH2:3][O:2][CH3:1])[C:12]=2[CH:13]=1)=[O:23])[CH:31]1[CH2:35][CH2:34][N:33]([C:36]([O:38][CH2:39][C:40]2[CH:41]=[CH:42][CH:43]=[CH:44][CH:45]=2)=[O:37])[CH2:32]1)([CH3:29])[CH3:28]참가 물질
3
실험 절차
Using 4-(4-methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid and benzyl 3-(isopropylamino)pyrrolidine-1-carboxylate, the title compound was obtained in a similar manner to Reference Example 5.
출처 및 근거
- ORD 기록
- ord-274d643e230a4effa50ee2daeef7ede7
- 출처 데이터셋
- uspto-grants-2013_03