N,N-dibenzyl-2-bromoethanamine → HCID 58375834, 화합물

반응식

[F:1][C:2]1[C:14]([C:15]#[N:16])=[CH:13][C:5]2[NH:6][C:7](=[O:12])[C:8]([CH3:11])([CH3:10])[O:9][C:4]=2[CH:3]=1.[CH2:17]([N:24]([CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[CH2:25][CH2:26]Br)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:28]([N:24]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:25][CH2:26][N:6]1[C:5]2[CH:13]=[C:14]([C:15]#[N:16])[C:2]([F:1])=[CH:3][C:4]=2[O:9][C:8]([CH3:11])([CH3:10])[C:7]1=[O:12])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1

참가 물질

반응물 2

HCID 14378N,N-dibenzyl-2-bromoethanamine

HCID 67330465HCID 67330465, 화합물

생성물 1

HCID 58375834HCID 58375834, 화합물

실험 절차

Using 7-fluoro-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonitrile and N,N-dibenzyl-2-bromoethanamine, the title compound was obtained in a similar manner to Reference Example 3.

출처 및 근거

ORD 기록: ord-82989e0021c049cd8465d6c0abb8abd3
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08389511B2

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