2,3-Dihydro[1,4]oxathiino[2,3-c]pyridine-7-carbaldehyde → 1-({4-[([1,3]oxathiolo[5,4-c]pyridin-6-ylmethyl)amino]-1-piperidinyl}methyl)-1,2-dihydro-4H,9H-imidazo[1,2,3-ij]-1,8-naphthyridine-4,9-dione

반응식

[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH:9]2[N:19]3[C:20]4[N:11]([C:12](=[O:22])[CH:13]=[CH:14][C:15]=4[CH:16]=[CH:17][C:18]3=[O:21])[CH2:10]2)[CH2:4][CH2:3]1.COC1N=C2C(CCC(=O)N2C[C@@H]2CO2)=CC=1.[S:40]1[C:49]2[CH:48]=[C:47]([CH:50]=O)[N:46]=[CH:45][C:44]=2[O:43][CH2:42]C1>>[S:40]1[C:49]2[CH:48]=[C:47]([CH2:50][NH:1][CH:2]3[CH2:3][CH2:4][N:5]([CH2:8][CH:9]4[N:19]5[C:20]6[N:11]([C:12](=[O:22])[CH:13]=[CH:14][C:15]=6[CH:16]=[CH:17][C:18]5=[O:21])[CH2:10]4)[CH2:6][CH2:7]3)[N:46]=[CH:45][C:44]=2[O:43][CH2:42]1