HCID 178418361, 화합물 → HCID 178461433, 화합물

HRID 1943913노트

반응식

HRID 1943913 반응식
[CH3:1][C@H:2]1[CH2:4][C@H:3]1[C:5]1[C:13]2[C:8](=[N:9][CH:10]=[C:11]([N+:14]([O-])=O)[CH:12]=2)[NH:7][N:6]=1.[H][H]>CO.[Pd]>[CH3:1][C@H:2]1[CH2:4][C@H:3]1[C:5]1[C:13]2[C:8](=[N:9][CH:10]=[C:11]([NH2:14])[CH:12]=2)[NH:7][N:6]=1

참가 물질

5

반응물 2

HCID 178418361HCID 178418361, 화합물HCID 178461434HCID 178461434, 화합물

생성물 1

HCID 178461433HCID 178461433, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

3-(cis-2-Methylcyclopropyl)-5-nitro-1H-pyrazolo[3,4-b]pyridine (0.0462 g, 0.212 mmol) and Pd/C were taken up in MeOH. Hydrogen gas was passed through for 10 minutes, and the reaction mixture was stirred under a hydrogen atmosphere for 20 minutes. The solution was filtered through celite and concentrated to provide 3-(cis-2-methylcyclopropyl)-1H-pyrazolo[3,4-b]pyridin-5-amine as an oil, which was used without further purification.

후처리

  1. customwas passed through for 10 minutes
  2. filtrationThe solution was filtered through celite and
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-98e2f883c1334237b6a9accd73e75a67
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394795B2

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