Methyl 2-(3-amino-4-chlorophenoxy)acetate → {8-Chloro-3-[4-(2,2-dimethylpropionyl)benzyl]-2-ethyl-4-oxo-1,4-dihydroquinolin-5-yloxy}acetic acid methyl ester

HRID 1944302노트

반응식

HRID 1944302 반응식
[CH3:1][O:2][C:3](=[O:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([NH2:13])[CH:7]=1.C([O:17][C:18](=O)[CH:19]([CH2:24][C:25]1[CH:30]=[CH:29][C:28]([C:31](=[O:36])[C:32]([CH3:35])([CH3:34])[CH3:33])=[CH:27][CH:26]=1)[C:20](=O)[CH2:21][CH3:22])C>>[CH3:1][O:2][C:3](=[O:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:7]=1[C:18](=[O:17])[C:19]([CH2:24][C:25]1[CH:26]=[CH:27][C:28]([C:31](=[O:36])[C:32]([CH3:34])([CH3:33])[CH3:35])=[CH:29][CH:30]=1)=[C:20]([CH2:21][CH3:22])[NH:13]2

참가 물질

3

반응물 2

HCID 66717604Methyl 2-(3-amino-4-chlorophenoxy)acetateHCID 674591252-[4-(2,2-Dimethylpropionyl)benzyl]-3-oxopentanoic acid ethyl ester

생성물 1

HCID 67456401{8-Chloro-3-[4-(2,2-dimethylpropionyl)benzyl]-2-ethyl-4-oxo-1,4-dihydroquinolin-5-yloxy}acetic acid methyl ester

실험 절차

The title compound was prepared by the method of Preparation 1c using (3-amino-4-chlorophenoxy)acetic acid methyl ester and 2-[4-(2,2-dimethylpropionyl)benzyl]-3-oxopentanoic acid ethyl ester.

출처 및 근거

ORD 기록
ord-dce8ab9482c34addad3595e18aa7f976
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394830B2

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