Water → Sodium 3-chlorobenzene-1-sulfinate
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])O.[Na+:16].S([O-])([O-])=O.[Na+].[Na+].O>O1CCOCC1>[Na+:16].[Cl:1][C:2]1[CH:3]=[C:4]([S:8]([O-:10])=[O:9])[CH:5]=[CH:6][CH:7]=1참가 물질
6
반응 조건
- 온도
- 75 °C
실험 절차
A solution of 3-chlorobenzenesulfonyl chloride (3.0 g) in dioxane (40 mL) was treated with a mixture of sodium hydrogen carbonate (2.7 g), sodium sulfite (3.6 g) and water (20 mL), and the resulting mixture was stirred at 75° C. for 30 minutes. The mixture was cooled to room temperature and concentrated under reduced pressure. The residue was triturated with ethanol to afford the title compound as a white solid (0.20 g).
후처리
- temperatureThe mixture was cooled to room temperature
- concentrationconcentrated under reduced pressure
- customThe residue was triturated with ethanol
출처 및 근거
- ORD 기록
- ord-f782cba467544f1285cd026dab12967c
- 출처 데이터셋
- uspto-grants-2013_03
- 특허 번호
- US08394836B2
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