Methyl 2-(5-chloro-2-methyl-1H-indol-1-yl)acetate → {5-Chloro-3-[3-(4-fluorobenzenesulfonyl)thiophen-2-ylmethyl]-2-methyl-indol-1-yl}acetic acid methyl ester
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[CH:15]=[CH:14][S:13][C:12]=2[CH:16]=O)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([Cl:31])=[CH:28][CH:29]=2)[CH:24]=[C:23]1[CH3:32]>>[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([Cl:31])=[CH:28][CH:29]=2)[C:24]([CH2:16][C:12]2[S:13][CH:14]=[CH:15][C:11]=2[S:8]([C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)(=[O:9])=[O:10])=[C:23]1[CH3:32]참가 물질
3
실험 절차
The title compound was prepared by the method of Preparation 29a using 3-(4-fluorobenzenesulfonyl)thiophene-2-carbaldehyde and (5-chloro-2-methylindol-1-yl)acetic acid methyl ester.
출처 및 근거
- ORD 기록
- ord-af3018d68ba14c5eb23471cc013fa756
- 출처 데이터셋
- uspto-grants-2013_03