Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → [3-(3-Benzenesulfonyl-5-methylthiophen-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester
반응식
[C:1]1([S:7]([C:10]2[CH:14]=[C:13]([CH3:15])[S:12][C:11]=2[CH:16]=O)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([F:31])=[CH:28][CH:29]=2)[CH:24]=[C:23]1[CH3:32]>>[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([F:31])=[CH:28][CH:29]=2)[C:24]([CH2:16][C:11]2[S:12][C:13]([CH3:15])=[CH:14][C:10]=2[S:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)(=[O:8])=[O:9])=[C:23]1[CH3:32]참가 물질
3
실험 절차
The title compound was prepared by the method of Preparation 29a using 3-benzenesulfonyl-5-methylthiophene-2-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.
출처 및 근거
- ORD 기록
- ord-70573cdf560746f39385e0637040b286
- 출처 데이터셋
- uspto-grants-2013_03