Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → [3-(4-Benzenesulfonyl-3-chloroisothiazol-5-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester

HRID 1944493노트

반응식

HRID 1944493 반응식
[CH3:1][O:2][C:3](=[O:16])[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][C:10]([F:14])=[CH:11][CH:12]=2)[CH:7]=[C:6]1[CH3:15].[C:17]1([S:23]([C:26]2[C:27]([Cl:33])=[N:28][S:29][C:30]=2[CH:31]=O)(=[O:25])=[O:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:1][O:2][C:3](=[O:16])[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][C:10]([F:14])=[CH:11][CH:12]=2)[C:7]([CH2:31][C:30]2[S:29][N:28]=[C:27]([Cl:33])[C:26]=2[S:23]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)(=[O:24])=[O:25])=[C:6]1[CH3:15]

참가 물질

3

반응물 2

HCID 58247161Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 866522134-Benzenesulfonyl-3-chloroisothiazole-5-carbaldehyde

생성물 1

HCID 67044606[3-(4-Benzenesulfonyl-3-chloroisothiazol-5-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester

실험 절차

The title compound was prepared by the method of Preparation 1c using (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester and 4-benzenesulfonyl-3-chloroisothiazole-5-carbaldehyde.

출처 및 근거

ORD 기록
ord-f7e2af2ddbf946ebbd68a6a9cfe5ade9
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394836B2

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