4-(Trifluoromethyl)benzenesulfonamide → Methyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylate

HRID 1944746

반응식

HRID 1944746 반응식
[CH3:1][O:2][C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][CH:7]([CH:8]3[NH2:15])[CH2:6]1)[CH2:12]2)=[O:4].[F:16][C:17]([F:29])([F:28])[C:18]1[CH:23]=[CH:22][C:21]([S:24](N)(=[O:26])=[O:25])=[CH:20][CH:19]=1.ClC1C=CC(S(N[C@H]2CC[C@H](C(OC)=O)CC2)(=O)=O)=CC=1[N+]([O-])=O>>[F:29][C:17]([F:16])([F:28])[C:18]1[CH:19]=[CH:20][C:21]([S:24]([NH:15][CH:8]2[CH:9]3[CH2:14][C:5]4([C:3]([O:2][CH3:1])=[O:4])[CH2:12][CH:11]([CH2:13][CH:7]2[CH2:6]4)[CH2:10]3)(=[O:26])=[O:25])=[CH:22][CH:23]=1

참가 물질

4

반응물 3

HCID 700184-(Trifluoromethyl)benzenesulfonamideHCID 57425932Methyl 4-aminoadamantane-1-carboxylateHCID 178501250HCID 178501250, 화합물

생성물 1

HCID 67225441Methyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylate

실험 절차

Methyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylate was prepared from 4-amino-adamantane-1-carboxylic acid methyl ester and 4-trifluoromethylbenzene sulfonamide using a method analogous to the method used to prepare Intermediate 1.

출처 및 근거

ORD 기록
ord-7884624e50b84549be58eff509fd4814
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394858B2

연결된 노트

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