4-Bromothiophenol → 6-((4-Bromophenyl)thio)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
반응식
BrC1C=C([S:8][C:9]2[CH:10]=[C:11]3[C:16](=[C:17]([CH3:19])[CH:18]=2)[N:15]=[CH:14][C:13]([C:20]([NH2:22])=[O:21])=[C:12]3[NH:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH3:31])[CH:25]=2)C=CC=1.[Br:32][C:33]1[CH:38]=[CH:37][C:36](S)=[CH:35][CH:34]=1>>[Br:32][C:33]1[CH:38]=[CH:37][C:36]([S:8][C:9]2[CH:10]=[C:11]3[C:16](=[C:17]([CH3:19])[CH:18]=2)[N:15]=[CH:14][C:13]([C:20]([NH2:22])=[O:21])=[C:12]3[NH:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH3:31])[CH:25]=2)=[CH:35][CH:34]=1참가 물질
3
실험 절차
The title compound was synthesized in a manner analogous to that described for Intermediate 59, using 4-bromothiophenol in place of 11-mercapto-1-undecanol. ES/MS calcd. for C24H21BrN3O2S+ 494.1. Found m/z=494.1 (M+H)+
출처 및 근거
- ORD 기록
- ord-34e84b058c6240468ef2fa5f55037dba
- 출처 데이터셋
- uspto-grants-2013_03