Sodium Sulfate → 2-Cyclohexen-1-one, 3-methyl-5-(1-methylethenyl)-

HRID 1945257노트

반응식

HRID 1945257 반응식
IC1C=CC=CC=1S([O-])(=O)=O.[Na+].OOS([O-])=O.[K+].S([O-])([O-])(=O)=O.[Na+].[Na+].[CH3:26][C:27]1[CH2:32][CH:31]([C:33]([CH3:35])=[CH2:34])[CH2:30][CH:29]([OH:36])[CH:28]=1>C(OCC)(=O)C>[CH3:26][C:27]1[CH2:32][CH:31]([C:33]([CH3:35])=[CH2:34])[CH2:30][C:29](=[O:36])[CH:28]=1

참가 물질

6

반응물 4

HCID 24436Sodium SulfateHCID 23662047Sodium 2-IodobenzenesulfonateHCID 23707502Potassium hydroxy sulfiteHCID 574220093-Methyl-5-(prop-1-en-2-yl)cyclohexa-2-enol

생성물 1

HCID 109972162-Cyclohexen-1-one, 3-methyl-5-(1-methylethenyl)-수율 91%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
70 °C

실험 절차

6.1 mg (0.02 mmol) of sodium 2-iodobenzenesulfonate prepared by Preparation Example 4, 0.49 g (0.8 mmol) of powdered Oxone (registered trademark), 0.5 g (3.5 mmol) of anhydrous sodium sulfate and 152 mg (1 mmol) of 3-methyl-5-(prop-1-en-2-yl)cyclohexa-2-enol were added to 5 ml of ethyl acetate, and the mixture was heated at 70° C. while being stirred under a nitrogen for eight hours. The later treatment was carried out in the same way as in Example 1, and then 3-methyl-5-(prop-1-en-2-yl)cyclohexa-2-enone was obtained. The yield of the obtained 3-methyl-5-(prop-1-en-2-yl)cyclohexa-2-enone was determined and the result is shown in Table 2. (Yield 91%)

출처 및 근거

ORD 기록
ord-9fa717455949404e94fe571a0f81f607
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394995B2

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