Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glutaric anhydride → 4-[(3-Ethynylphenyl)carbamoyl]butanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glutaric anhydride | HCID 7940 | — |
| 반응물 | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(3-Ethynylphenyl)carbamoyl]butanoic acid | HCID 43529240 | 99% |
반응 단계
Glutaric anhydride (215 mg, 1.9 mmol) was dissolved in anhydrous dichloromethane (7 ml) and followed by the addition of 3-ethynylaniline (200 mg, 1.7 mmol). The mixture was allowed to stir at room temperature for 6 hours before the solvent was evaporated under reduced pressure to provide the product as a white solid (363 mg, 99%);
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745229B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-b51d7cb6b41e41718e3f39d76b7da4bc |
| 출처 메모 | uspto-grants-2010_06 |