2,6-Difluoro-N-(1H-pyrazol-3-yl)benzamide (for a preparation see Intermediate 9)(174 mg, 0.78 mmol) was dissolved in DMF (2.5 ml). Sodium iodide (33 mg, 0.22 mmol) and potassium carbonate (164 mg, 1.19 mmol) were added followed by 2-(bromomethyl)-4-chloro-1-[(phenylmethyl)oxy]benzene (synthesised according to WO2006066968) (233 mg, 0.75 mmol) washed in with further DMF (2.5 ml). The reaction mixture was stirred at ambient temperature overnight. The reaction mixture was then stirred and heated to 80° C. for 3 h under a nitrogen atmosphere and allowed to cool. Further 2-(bromomethyl)-4-chloro-1-[(phenylmethyl)oxy]benzene (51 mg) was added, and the reaction was stirred and heated to 80° C. under a nitrogen atmosphere for 3 h. The reaction mixture was concentrated in vacuo. The crude material was treated with water (50 ml) and extracted with EtOAc (3×50 ml). The extracts were combined, dried (MgSO4) and concentrated in vacuo. The residue was purified on silica (50 g) using 0-100% EtOAc-cyclohexane. Appropriate fractions were concentrated in vacuo to give the title compound as a colourless gum (20 mg);
