4-Aminophenol → 6-(cyclopentylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide

HRID 1946706노트

반응식

HRID 1946706 반응식
[CH:1]1([NH:6][C:7]2[N:12]=[CH:11][N:10]=[C:9]([C:13]([OH:15])=O)[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:16][C:17]1[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=1>C(#N)C>[CH:1]1([NH:6][C:7]2[N:12]=[CH:11][N:10]=[C:9]([C:13]([NH:16][C:17]3[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=3)=[O:15])[CH:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

참가 물질

4

반응물 2

HCID 4034-AminophenolHCID 594470556-(Cyclopentylamino)pyrimidine-4-carboxylic acid2회

생성물 1

HCID 251826236-(cyclopentylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Following the general method as outlined in Example 1, starting from 6-[(cyclopentyl)amino]pyrimidine-4-carboxylic acid (Intermediate 5) and 4-aminophenol (Aldrich), the title compound was obtained as a yellow solid after trituration in acetonitrile.

출처 및 근거

ORD 기록
ord-eaaeb7fa30d441efb8faf1b9d17cebb4
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399448B2

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