7-Amino-4-methoxy-2-methyl-2,3-dihydroisoindol-1-one → 7-Amino-2-methyl-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one

HRID 1948015노트

반응식

HRID 1948015 반응식
NC1C=CC(OC)=C2C=1C(=O)N(C)C2.[CH3:15][N:16]1[CH2:24][C:23]2[C:18](=[C:19]([N+:29]([O-])=O)[CH:20]=[CH:21][C:22]=2[O:25][CH:26]([CH3:28])[CH3:27])[C:17]1=[O:32]>>[NH2:29][C:19]1[CH:20]=[CH:21][C:22]([O:25][CH:26]([CH3:28])[CH3:27])=[C:23]2[C:18]=1[C:17](=[O:32])[N:16]([CH3:15])[CH2:24]2

참가 물질

3

반응물 2

HCID 672539417-Amino-4-methoxy-2-methyl-2,3-dihydroisoindol-1-one2회HCID 672547622-Methyl-7-nitro-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one2회

생성물 1

HCID 672558647-Amino-2-methyl-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one

실험 절차

The title compound was prepare according to the procedure for 7-Amino-4-methoxy-2-methyl-2,3-dihydro-1H-isoindol-1-one (Compound 205A) using 2-Methyl-7-nitro-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one (Compound 207B). MS (ES+): m/z 222.21 (100) [MH+]; HPLC: tR=0.93 min (UPLC, analytical).

출처 및 근거

ORD 기록
ord-4dece53e18384c15b2f3addff86a4efe
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399433B2

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