Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | (3R)-(2-adamantyl) 3-(tert-butoxycarbonylamino)pyrrolidine-1-carboxylate | HCID 52944645 | — |
| 생성물 | (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt | HCID 67155574 | — |
반응 단계
To (3R)-(2-adamantyl) 3-(tert-butoxycarbonylamino)pyrrolidine-1-carboxylate (0.43 g, 1.18 mmol) was added 4 M HCl in dioxane (5 mL, 20 mmol). The mixture was stirred at rt for 1 h and concentrated to afford (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt (0.45 g) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08399504B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-2f277e339d874a67bc612ea95ef63068 |
| 출처 메모 | uspto-grants-2013_03 |