Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1948820생성일: 2026년 10월 26일
1-Phenethylamine, (+)- → (R)-1-phenylethanaminium (1S,3aR,6aS)-2(t-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-1-carboxylate
https://huagongshe.com/reaction/1948820
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Phenethylamine, (+)- | HCID 643189 | — |
| 반응물 | 2-(Tert-butoxycarbonyl)octahydrocyclopenta[C]pyrrole-1-carboxylic acid | HCID 53249646 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | (R)-1-phenylethanaminium (1S,3aR,6aS)-2(t-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-1-carboxylate | HCID 87377471 | — |
반응 단계
To a solution of racemic N-t-butyloxycarbonyl-3-azabicyclo[3.3.0]octane-2-carboxylic acid (4.66 g) in ethyl acetate (100 mL) was added (R)-α-methylbenzylamine (56.7 g) and the solution was stirred for 16 hr at 22-25° C. The mixture was filtered and the solids were rinsed with ethyl acetate. The solids were dried at 20-30° C. under vacuum for 4 hours to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08399615B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_03 |
|---|
| ORD ID | ord-cbb687bcc33b4b90aedd98f2792be8ff |
|---|
| 출처 메모 | uspto-grants-2013_03 |
|---|
