Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → NCS Chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | 2-Fluoro-6-methylpyridine | HCID 96090 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | NCS Chloride | HCID 86612418 | — |
반응 단계
2-Fluoro-6-methylpyridine (1.11 g, 10 mmol), NCS (2.0 g, 15 mmol), and catalytic benzoyl peroxide were dissolved in benzene and heated to reflux overnight. The reaction was concentrated and diluted with water and EtOAc. The organic layer was washed with saturated aq. NaHCO3, dried, filtered, and concentrated. The residue was purified on silica gel to give the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08399666B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-94a2fa2460e1453fba81f36f1079e633 |
| 출처 메모 | uspto-grants-2013_03 |