Potassium Carbonate → 4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[1-(N,N-dimethylcarbamoylmethyl)piperidin-3-yloxy]quinazoline

반응식

Cl[CH2:2][C:3]([N:5]([CH3:7])[CH3:6])=[O:4].Cl.Cl.[Cl:10][C:11]1[C:12]([F:37])=[C:13]([CH:34]=[CH:35][CH:36]=1)[NH:14][C:15]1[C:24]2[C:19](=[CH:20][C:21]([O:32][CH3:33])=[C:22]([O:25][CH:26]3[CH2:31][CH2:30][CH2:29][NH:28][CH2:27]3)[CH:23]=2)[N:18]=[CH:17][N:16]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[Cl:10][C:11]1[C:12]([F:37])=[C:13]([CH:34]=[CH:35][CH:36]=1)[NH:14][C:15]1[C:24]2[C:19](=[CH:20][C:21]([O:32][CH3:33])=[C:22]([O:25][CH:26]3[CH2:31][CH2:30][CH2:29][N:28]([CH2:2][C:3](=[O:4])[N:5]([CH3:7])[CH3:6])[CH2:27]3)[CH:23]=2)[N:18]=[CH:17][N:16]=1