HCID 58277326, 화합물 → HCID 58277424, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

참가 물질

반응물 2

HCID 58277326HCID 58277326, 화합물

HCID 58277462HCID 58277462, 화합물

생성물 1

HCID 58277424HCID 58277424, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 53A in analogy to the synthesis of the compound of Example 71A. 515 mg (93% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-b49f93aad88345b38ae72ce5e19db5c9
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

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