HCID 58277303, 화합물 → HCID 58277391, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([O:23]CC)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([OH:23])=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 58277303HCID 58277303, 화합물

HCID 58277326HCID 58277326, 화합물

생성물 1

HCID 58277391HCID 58277391, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 58A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 1.64 g (100% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-a086a41e93b44782bcd8fcdd5a306075
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

반응 노트

불러오는 중…