HCID 58277326, 화합물 → HCID 58277320, 화합물

HRID 1949266노트

반응식

HRID 1949266 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]#[N:20])[CH:14]=3)[N:11]=[C:10]([C:21]([O:23]CC)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]#[N:20])[CH:14]=3)[N:11]=[C:10]([C:21]([OH:23])=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 58277326HCID 58277326, 화합물HCID 58277449HCID 58277449, 화합물

생성물 1

HCID 58277320HCID 58277320, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 61A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 470 mg of the title compound with 77% purity are obtained.

출처 및 근거

ORD 기록
ord-855dab1d5e0f4b0485e023a7bc47eb0b
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399682B2

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