HCID 58277326, 화합물 → HCID 58277461, 화합물

HRID 1949272노트

반응식

HRID 1949272 반응식
C([O:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[C:11]([C:15]2[N:19]([C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=3)[N:18]=[C:17]([C:27]([O:29]CC)=[O:28])[CH:16]=2)[CH:12]=[CH:13][CH:14]=1)(=O)C.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:26][C:22]1[CH:21]=[C:20]([N:19]2[C:15]([C:11]3[CH:12]=[CH:13][CH:14]=[C:9]([O:8][CH2:7][CH2:6][CH2:5][OH:4])[CH:10]=3)=[CH:16][C:17]([C:27]([OH:29])=[O:28])=[N:18]2)[CH:25]=[CH:24][CH:23]=1

참가 물질

3

반응물 2

HCID 58277326HCID 58277326, 화합물HCID 58277434HCID 58277434, 화합물

생성물 1

HCID 58277461HCID 58277461, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 67A in analogy to the synthesis of the compound of Example 71A. 99 mg of the title compound with 65% purity (70% of theory) are obtained.

출처 및 근거

ORD 기록
ord-43a6b14e29d546baac9f6b744560e40e
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399682B2

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