4-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]- → HCID 44230124, 화합물

HRID 1949282노트

반응식

HRID 1949282 반응식
ClC1C=C(N2C(C3C=CC=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1.[Cl:23][C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[C:40](F)[CH:39]=[C:38]([Cl:43])[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][C:29]=1F>>[Cl:23][C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[CH:40][CH:39]=[C:38]([Cl:43])[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][CH:29]=1

참가 물질

3

반응물 2

HCID 442301814-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]-HCID 58277345HCID 58277345, 화합물

생성물 1

HCID 44230124HCID 44230124, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 74A in analogy to the synthesis of the compound of Example 1. 110 mg (91% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록
ord-c4005767797444d495652a99414aff02
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399682B2

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