4-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]- → HCID 44230183, 화합물

HRID 1949285노트

반응식

HRID 1949285 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([C:20]([F:23])([F:22])[F:21])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([C:20]([F:21])([F:23])[F:22])[CH:14]=3)=[CH:11][C:10]([C:24]([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=[O:26])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 442301814-Imidazolidinone, 1-[[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl]-HCID 58277417HCID 58277417, 화합물

생성물 1

HCID 44230183HCID 44230183, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 77A in analogy to the synthesis of the compound of Example 1. 28 mg (74% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록
ord-fdfdf10ec16a490a93300b17a9127b41
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399682B2

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