Aic-292 → HCID 58277270, 화합물

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[F:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[N:11]=[C:10]([C:21](O)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[N:11]=[C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 44230181Aic-292

HCID 58277379HCID 58277379, 화합물

생성물 1

HCID 58277270HCID 58277270, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 80A in analogy to the synthesis of the compound of Example 1. 27 mg (70% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-9ae0dc65566c40b7b6b57f0e3bc8c2d4
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

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