Aic-292 → HCID 58277415, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[F:19])=[CH:11][C:10]([C:20]([OH:22])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[F:19])=[CH:11][C:10]([C:20]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 44230181Aic-292

HCID 58277359HCID 58277359, 화합물

생성물 1

HCID 58277415HCID 58277415, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 86A in analogy to the synthesis of the compound of Example 1. 34 mg (88% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-2bd76d676f1749058f0472e4b2af3d00
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

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