Aic-292 → HCID 58277405, 화합물

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FC1C=C(C2N(C3C=CC(F)=CC=3)N=C(C(O)=O)C=2)C=CC=1.Cl[C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[C:40]([F:42])[CH:39]=[C:38](Cl)[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][C:29]=1[F:30]>>[F:42][C:40]1[CH:41]=[C:36]([C:35]2[N:31]([C:26]3[CH:25]=[CH:24][C:29]([F:30])=[CH:28][CH:27]=3)[N:32]=[C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])[CH:34]=2)[CH:37]=[CH:38][CH:39]=1

참가 물질

반응물 2

HCID 44230181Aic-292

HCID 58277404HCID 58277404, 화합물

생성물 1

HCID 58277405HCID 58277405, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 90A in analogy to the synthesis of the compound of Example 1. 18 mg (47% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-181e4b95776c49349cf6ef61b3e26031
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

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