HCID 58277360, 화합물 → HCID 58277269, 화합물

HRID 1949303노트

반응식

HRID 1949303 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[C:15]([F:23])[CH:14]=3)=[CH:11][C:10]([C:24](O)=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:51]3[CH2:55][C:54](=[O:56])[NH:53][CH2:52]3)=O)=N2)C=CC=1>C(O)=O>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[C:15]([F:23])[CH:14]=3)=[CH:11][C:10]([C:24]([N:51]3[CH2:55][C:54](=[O:56])[NH:53][CH2:52]3)=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 58277360HCID 58277360, 화합물HCID 58277365HCID 58277365, 화합물

생성물 1

HCID 58277269HCID 58277269, 화합물

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

The preparation of the title compound takes place starting from the compound of Example 97A in analogy to the synthesis of the compound of Example 23 with the addition of 0.1% formic acid in the preparative HPLC. 60 mg (51% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록
ord-6e8d5a9681094fe8b17b84924db455df
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399682B2

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