Aic-292 → HCID 44230249, 화합물

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[F:1][C:2]([F:29])([F:28])[C:3]1[CH:4]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([OH:27])=O)[CH:14]=2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:53]3[CH2:57][C:56](=[O:58])[NH:55][CH2:54]3)=O)=N2)C=CC=1F>>[F:11][C:9]([F:12])([F:10])[C:7]1[CH:6]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([N:53]3[CH2:57][C:56](=[O:58])[NH:55][CH2:54]3)=[O:27])[CH:14]=2)[CH:4]=[C:3]([C:2]([F:1])([F:28])[F:29])[CH:8]=1

참가 물질

반응물 2

HCID 44230181Aic-292

HCID 58277463HCID 58277463, 화합물

생성물 1

HCID 44230249HCID 44230249, 화합물

실험 절차

The preparation of the title compound takes place starting from the compound of Example 103A in analogy to the synthesis of the compound of Example 1. 26 mg (72% of theory) of the title compound are obtained.

출처 및 근거

ORD 기록: ord-2e95d4dc03de4e4384b03bb356c1604c
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399682B2

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