1H-Indazole-5-carboxaldehyde → 1-(4-Bromo-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

반응식

[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19]Br)=[C:15]([C:21]([F:24])([F:23])[F:22])[CH:14]=1>>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][N:1]2[C:9]3[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=3)[CH:3]=[N:2]2)=[C:15]([C:21]([F:22])([F:23])[F:24])[CH:14]=1

참가 물질

반응물 2

HCID 212506441H-Indazole-5-carboxaldehyde

HCID 534180314-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene

생성물 1

HCID 866545531-(4-Bromo-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

실험 절차

1-(4-Bromo-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-indazole-5-carbaldehyde and 4-bromo-1-bromomethyl-2-trifluoromethyl-benzene following General Procedure A.

출처 및 근거

ORD 기록: ord-5bb206ee029e405cac1e3705893d6486
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399681B2

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