2-Bromo-1-(bromomethyl)-4-(trifluoromethyl)benzene → 1-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

반응식

[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.[Br:12][C:13]1[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:15][C:14]=1[CH2:23]Br>>[Br:12][C:13]1[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[CH:15][C:14]=1[CH2:23][N:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1

참가 물질

반응물 2

HCID 149499362-Bromo-1-(bromomethyl)-4-(trifluoromethyl)benzene

HCID 212506441H-Indazole-5-carboxaldehyde

생성물 1

HCID 866545541-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

실험 절차

1-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-indazole-5-carbaldehyde and 2-bromo-1-bromomethyl-4-trifluoromethyl-benzene following General Procedure A.

출처 및 근거

ORD 기록: ord-7021c6085a44405f8c1ee8475a9d4e95
출처 데이터셋: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08399681B2

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