Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Piperidinecarboxylic acid → 1-(4-Oxo-4,5-dihydro-thiazol-2-yl)piperidine-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Piperidinecarboxylic acid | HCID 3773 | — |
| 반응물 | 2-(Methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-one | HCID 1482022 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-(4-Oxo-4,5-dihydro-thiazol-2-yl)piperidine-4-carboxylic acid | HCID 67240640 | — |
반응 단계
To a solution of 2-methylsulfanyl-thiazol-4-one (4.4 g, 30 mmol) in MeOH (60 mL) was added piperidine-4-carboxylic acid (3.9 g, 30 mmol). The mixture was stirred at room temperature for 16 hours. The resulting solid was collected by filtration, washed with fresh MeOH and dried to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08399681B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-72f7a526c84c4e3faa7d653322bc5d49 |
| 출처 메모 | uspto-grants-2013_03 |